University of Rochester

education📍 Rochester, United States
University of Rochester
2
Alpha-gal Syndrome Publications
1
Alpha-gal Syndrome Researchers

Associated Institutions

Strong Memorial Hospital
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University of Rochester Medicine
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Highland Hospital
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Materials Science in Extreme Environments University Research Alliance
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Laboratory for Laser Energetics
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Alpha-gal Syndrome Researchers

Publications

American College of Allergy, Asthma and Immunology (ACAAI)/American Academy of Pediatrics (AAP) symposium-What was served in the past year: Food allergy nontreatment.

Bingemann TA
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology •

Food allergies are increasing, with 1 of 13 children in the United States affected. This article discusses articles chosen by the author for inclusion in the American College of Allergy, Asthma and Immunology/American Academy of Pediatrics Symposium Hot Topics in Pediatric Allergy and Immunology, specifically on updates in food allergy nontreatment, and provides a focused review with Podium to Practice Takeaways for each article. Food allergies with delayed presentation of symptoms from the time of exposure, such as food protein-induced enterocolitis syndrome and alpha-gal syndrome (AGS), are highlighted. Both food allergies are increasingly seen by clinicians. Food challenges play an important role in the diagnosis, management, and resolution of these conditions. As such, clinicians should understand the pattern of reaction severity over time in food protein-induced enterocolitis syndrome to assist families in deciding when, where, and how oral food challenges should be scheduled. Regarding AGS, it is imperative that physicians understand risk factors for the development of alpha-gal sensitization and the expected symptomatology. In addition, clinicians need to provide counseling that allows for appropriate but not excessive food avoidance based on allergenicity. Finally, the article addresses the concern that has arisen about the safety of gelatin-containing vaccines in patients with AGS and reports that reactions to gelatin-containing vaccines seem to be rare.

Diagnostic Challenges in Anaphylaxis.

Lieberman JA, Bingemann TA, Wang J
The journal of allergy and clinical immunology. In practice •

Anaphylaxis is a severe and potentially life-threatening allergic reaction. Since its discovery over 100 years ago, research has led to great strides in describing pathophysiologic mechanisms of anaphylaxis; however, there is still imprecision regarding its definition and a lack of reliable, confirmatory testing. In this paper, we review definitions of anaphylaxis, highlighting studies examining the utility of the current clinical consensus definition. In addition, we evaluate current difficulties and limitations for both providers in acute care settings managing episodes and allergists evaluating patients after an episode has resolved. Finally, we provide an algorithm for outpatient evaluation of patients with a history of possible anaphylaxis.